Substance Grouping

The main objective of WP5: Substance Grouping is to address the central hypothesis that grouping persistent and mobile substances based on specific molecular substructures will support persistent and mobile substance prioritization and directed risk assessment procedures.

This will be achieved through the following sub-objectives: 

Develop and apply a novel method of grouping persistent and mobile substances.

Compile information on uses, emissions, circularity and environmental monitoring of these persistent and mobile substances and their alternatives, as a robust, updatable, open-access data set.

Apply this data for persistent and mobile alternatives assessment and safe-and-sustainable by design strategies.

Implement the persistent and mobile substance grouping system as part of an early warning system for persistent and mobile substance groups of emerging concern.

Initial substance groups prioritized by WP5

The Team

To tackle all PM substances on the global chemical inventory, WP5 involves three partners. The WP is led by Dr. Hans Peter Arp at the Norwegian Geotechnical Institute who has worked to develop the science behind the PMT/vPvM criteria. NGI will collaborate with the University of Luxembourg and EMPA who will use their expertise in (open) big data approaches to solve urgent environmental chemistry problems. The database manager for this WP is Dr. Raoul Wolf (NGI).

Coordination & Substance Grouping in ZeroPM: Meet the NGI Oslo team
Transformational Cheminformatics in ZeroPM: Meet the WP5 team at Universite du Luxembourg (
Tackling the Global Chemical Inventory in ZeroPM: Meet the EMPA St. Gallen Team
Norwegian Geotechnical Institute (NGI)
University of Luxembourg (
Swiss Federal Laboratories for
Materials Science and Technology (EMPA)